@ARTICLE{Granica_Sebastian_Polyphenol_2013, author={Granica, Sebastian and Piwowarski, Jakub P. and Kiss, Anna K.}, volume={vol. 55}, number={No 1}, journal={Acta Biologica Cracoviensia s. Botanica}, howpublished={online}, year={2013}, publisher={Biological Commission of the Polish Academy of Sciences – Cracow Branch}, abstract={The chemical composition and bioactivity of a water/methanol extract prepared from aerial parts of Circaea lutetiana were determined. HPLC-DAD-MS3 analysis revealed the presence of 14 different compounds comprising phenolic acids, ellagitannins and flavonoids. Antioxidant assays showed the extract's strong scavenging activity towards DPPH (SC50 33.1±3.1 μg/ml), O2 - (SC50 4.0±2.3 μg/ml) and H2O2 (SC50 below 2 μg/ml). Enzyme-based studies revealed that Circaea lutetiana extract inhibits the activity of hyaluronidase (IC50 13.3±2.4 μg/ml) and lipoxygenase (IC50 44.7±1.4 μg/ml). These results support some traditional uses of Circaea lutetiana.}, type={Artykuły / Articles}, title={Polyphenol Composition of Extract from Aerial Parts of Circaea Lutetiana L. and its Antioxidant and Anti-Inflammatory Activity in Vitro}, URL={http://ochroma.man.poznan.pl/Content/81780/PDF/02_granica.pdf}, doi={10.2478/abcsb-2013-0005}, keywords={Circaea lutetiana, enchanter's nightshade, lipoxygenase, hyaluronidase, antioxidant activity}, }