Szczegóły

Tytuł artykułu

Comparative evaluation of single and combined efficacy of dipyridamole, ketotifen and quercetin on cyclosporine induced hepatorenal toxicity

Tytuł czasopisma

Polish Journal of Veterinary Sciences

Rocznik

2023

Wolumin

vol. 26

Numer

No 4

Afiliacje

Dik, B. : Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Selcuk University, Ardicli Neighborhood, 42130, Konya, Turkey ; Parlak, T.M. : Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Selcuk University, Ardicli Neighborhood, 42130, Konya, Turkey ; Tufan, O. : Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Selcuk University, Ardicli Neighborhood, 42130, Konya, Turkey ; Er, A. : Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Selcuk University, Ardicli Neighborhood, 42130, Konya, Turkey ; Ozgur, F.B. : Harran University, Birecik Vocational School, Laboratory and Veterinary Health Program, Karsiyaka Neighborhood, Prof. Dr. İbrahim Halil MUTLU Avenue, 63400, Sanliurfa, Turkey

Autorzy

Słowa kluczowe

hepatorenal toxicity ; cyclosporine ; ketotifen ; dipyridamole ; quercetin

Wydział PAN

Nauki Biologiczne i Rolnicze

Zakres

549-557

Wydawca

Polish Academy of Sciences Committee of Veterinary Sciences ; University of Warmia and Mazury in Olsztyn

Bibliografia

1. Abdel-Raheem IT, Abdel-Ghany AA, Mohamed GA (2009) Protective effect of quercetin against gentamicin-induced nephrotoxicity in rats. Bio Pharm Bull 32: 61-67.
2. Abdelzaher WY, AboBakr Ali AH, El-Tahawy NF (2020) Mast cell stabilizer modulates Sirt1/Nrf2/TNF pathway and inhibits oxidative stress, inflammation, and apoptosis in rat model of cyclophosphamide hepatotoxicity. Immunopharmacol Immunotoxicol 42: 101-109.
3. Aizawa T, Suzuki S, Asawa T, Komatsu M, Shigematsu S, Okada N, Katakura M, Hiramatsu K, Shinoda T, Hashizume K (1990) Di-pyridamole reduces urinary albumin excretion in diabetic patients with normo- or microalbuminuria. Clin Nephrolp 33: 130-135.
4. Amudha G, Josephine A, Varalakshmi P (2006) Role of lipoic acid in reducing the oxidative stress induced by cyclosporine A. Clin Chim Acta 372: 134-139.
5. Andreucci M, Faga T, Pisani A, Perticone M, Michael A (2017) The ischemic/nephrotoxic acute kidney injury and the use of renal bi-omarkers in clinical practice. Eur J Inter Med 39: 1-8.
6. Aydın B (2011) Quercetin prevents methotrexate-induced hepatotoxicity without interfering methotrexate metabolizing enzymes in liver of mice. J Appl Biol Sci 5: 75-80.
7. Balah A, Ezzat O, Akool ES (2018) Vitamin E inhibits cyclosporin A-induced CTGF and TIMP-1 expression by repressing ROS-mediated activation of TGF-beta/Smad signaling pathway in rat liver. Int Immunopharmacol 65: 493-502.
8. Balakumar P, WitnessKoe WE, Gan YS, JemayPuah SM, Kuganesswari S, Prajapati SK, Varatharajan R, Jayachristy SA, Sundram K, Bahari MB (2017) Effects of pre and post-treatments with dipyridamole in gentamicin-induced acute nephrotoxicity in the rat. Regul Toxicol Pharmacol 84: 35-44.
9. Behling EB, Sendao MC, Francescato HD, Antunes LM, Costa RS, Bianchi Mde L (2006) Comparative study of multiple dosage of quercetin against cisplatin-induced nephrotoxicity and oxidative stress in rat kidneys. Pharmacol Rep 58: 526-532.
10. Burdmann EA, Andoh TF, Yu L, Bennett WM (2003) Cyclosporine nephrotoxicity. Semin Nephrol 23: 465-476.
11. Carlos CP, Sonehara NM, Oliani SM, Burdmann EA (2014) Predictive usefulness of urinary biomarkers for the identification of cyclo-sporine A-induced nephrotoxicity in a rat model. PLoS One 9: e103660.
12. Chakrabarti S, Vitseva O, Iyu D, Varghese S, Freedman JE (2005) The effect of dipyridamole on vascular cell-derived reactive oxygen species. J Pharmacol Exp Ther 315: 494-500.
13. Chinen R, Camara NO, Nishida S, Silva MS, Rodrigues DA, Pereira AB, Pacheco-Silva A (2006) Determination of renal function in long-term heart transplant patients by measurement of urinary retinol-binding protein levels. Brazil J Med Biol Res 39: 1305-1313.
14. Daoudaki M, Fouzas I, Stapf V, Ekmekcioglu C, Imvrios G, Andoniadis A, Demetriadou A, Thalhammer T (2003) Cyclosporine a augments P-glycoprotein expression in the regenerating rat liver. Biol Pharm Bull 26: 303-307.
15. El-Bassossy HM, Eid BG (2018) Cyclosporine A exhibits gender-specific nephrotoxicity in rats: Effect on renal tissue inflammation. Biochem Biophys Res Commun 495: 468-472.
16. El-Shafey MM, Abd-Allah GM, Mohamadin AM, Harisa GI, Mariee AD (2015) Quercetin protects against acetaminophen-induced hepatorenal toxicity by reducing reactive oxygen and nitrogen species. Pathophysiology 22: 49-55.
17. Hagar HH (2004) The protective effect of taurine against cyclosporine A-induced oxidative stress and hepatotoxicity in rats. Toxicol Lett 151: 335-343.
18. Hutchinson MR, Loram LC, Zhang Y, Shridhar M, Rezvani N, Berkelhammer D, Phipps S, Foster PS, Landgraf K, Falke JJ, Rice KJ, Maier SF, Yin H, Watkins LR (2010) Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity. Neuroscience 168: 551-563.
19. Josephine A, Amudha G, Veena CK, Preetha SP, Varalakshmi P (2007) Oxidative and nitrosative stress mediated renal cellular damage induced by cyclosporine A: role of sulphated polysaccharides. Biol Pharm Bull 30: 1254-1259.
20. Kaur T, Kaur A, Singh M, Buttar HS, Pathak D, Singh AP (2016) Mast cell stabilizers obviate high fat diet-induced renal dysfunction in rats. Eur J Pharmacol 777: 96-103.
21. Khattab HA, Abounasef SK, Bakheet HL (2019) The biological and hematological effects of Echinacea purpurea L. roots extract in the immunocompromised rats with cyclosporine. J Microsc Ultrastruct 7: 65-71.
22. Lei DM, Piao SG, Jin YS, Jin H, Cui ZH, Jin HF, Jin JZ, Zheng HL, Li JJ, Jiang YJ, Yang CW , Li C (2014) Expression of erythropoi-etin and its receptor in kidneys from normal and cyclosporine-treated rats. Transplant Proc 46: 521-528.
23. Lesjak M, Beara I, Simin N, Pintać D, Majkić T, Bekvalac K, Orčić D, Mimica-Dukić N (2018) Antioxidant and antiinflammatory activi-ties of quercetin and its derivatives. J Funct Food 40: 68-75.
24. Lloberas N, Torras J, Alperovich G, Cruzado JM, Gimenez-Bonafe P, Herrero-Fresneda I, Franquesa LM, Rama I, Grinyo JM (2008) Different renal toxicity profiles in the association of cyclosporine and tacrolimus with sirolimus in rats. Nephrol Dial Transplant 23: 3111-3119.
25. Marchewka Z, Kuźniar J, Długosz A, Krasnowski R, Zynek-Litwin M, Stokłosa A, Klinger M (2007) Limitations of cyclosporine tox-icity assessment in early stage after renal transplantation. Acta Toxicol 15: 17-24.
26. Mokbel S (2000) Effects of dipyridamole and nifedipine on experimentally-induced hepatotoxicity by carbon-tetrachloride in rats. Mansoura Med J 29: 43-53.
27. Morales AI, Vicente-Sanchez C, Santiago Sandoval JM, Egido J, Mayoral P, Arévalo MA, Fernández-Tagarro M, López-Novoa JM, Pérez-Barriocanal F (2006) Protective effect of quercetin on experimental chronic cadmium nephrotoxicity in rats is based on its antioxi-dant properties. Food Chem Toxicol 44: 2092-2100.
28. Mostafavi-Pour Z, Zal F, Monabati A, Vessal M (2008) Protective effects of a combination of quercetin and vitamin E against cyclo-sporine A-induced oxidative stress and hepatotoxicity in rats. Hepatol Res 38: 385-392.
29. Palomero J, Galan AI, Munoz ME, Tunon MJ, Gonzalez-Gallego J, Jimenez R (2001) Effects of aging on the susceptibility to the toxic effects of cyclosporin A in rats. Changes in liver glutathione and antioxidant enzymes. Free Radic Biol Med 30: 836-845.
30. Perez-Rojas J, Blanco JA, Cruz C, Trujillo J, Vaidya VS, Uribe N, Bonventre JV, Gamba G, Bobadilla NA (2007) Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity. Am J Physiol Renal Physiol, 292: F131-139.
31. Refaie M, Ibrahim S, Sadek SA, Abdelrahman A (2017) Role of ketotifen in methotrexate-induced nephrotoxicity in rats. Egypt J Basic Clin Pharmacol 7: 70-80.
32. Sereno J, Vala H, Nunes S, Rocha-Pereira P, Carvalho E, Alves R, Teixeira F, Reis F (2015). Cyclosporine A-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat. J Physiol Pharmacol 66: 285-299.
33. Seven I, Baykalır BG, Seven PT, Dagoglu G (2014) The ameliorative effects of propolis against cyclosporine A induced hepatotoxicity and nephrotoxicity in rats. Kafkas Univ Vet Fak Derg 20: 641-648.
34. Vangaveti S, Das P, Kumar VL (2021) Metformin and silymarin afford protection in cyclosporine A induced hepatorenal toxicity in rat by modulating redox status and inflammation. J Biochem Molecular Toxicol 35: e22614.
35. Wei Y, Luo Z, Zhou K, Wu Q, Xiao W, Yu Y, Li T (2021) Schisandrae chinensis fructus extract protects against hepatorenal toxicity and changes metabolic ions in cyclosporine A rats. Nat Prod Res 35: 2915-2920.
36. Weyrich AS, Denis MM, Kuhlmann-Eyre JR, Spencer ED, Dixon DA, Marathe GK, McIntyre TM, Zimmerman GA, Prescott SM (2005) Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates. Circulation 111: 633-642.
37. Wu Q, Wang X, Nepovimova E, Wang Y, Yang H, Kuca K (2018) Mechanism of cyclosporine A nephrotoxicity: Oxidative stress, au-tophagy, and signalings. Food Chem Toxicol 118: 889-907.
38. Yuksel Y, Yuksel R, Yagmurca M, Haltas H, Erdamar H, Toktas M, Ozcan O (2017) Effects of quercetin on methotrexate-induced ne-phrotoxicity in rats. Hum Exp Toxicol 36: 51-61.

Data

2023.12.12

Typ

Article

Identyfikator

DOI: 10.24425/pjvs.2023.148275 ; ISSN 1505-1773
×