Nauki Techniczne

Archives of Acoustics

Zawartość

Archives of Acoustics | Online first

Abstrakt

This study introduces a proof-of-concept methodology for evaluating pressure-dependent non-linear acoustic properties of liver tissue. The proposed non-linearity index (NLI) is derived from echo amplitudes obtained at two substantially different acoustic pressures. Unlike previous harmonic-based approaches, the method relies solely on the fundamental frequency band, allowing clinical implementation without additional system modifications. The NLI is estimated as a ratio of local amplitudes of the amplified low-pressure image (ALPI) to the high-pressure image (HPI). Experimental validation includes hydrophone measurements, k-Wave simulations, and in vivo imaging of healthy and fatty livers. The results demonstrate that NLI values increase with the degree of steatosis, in agreement with theoretical expectations based on tissue B/A coefficients.
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Autorzy i Afiliacje

Andrzej Nowicki
1
Jurij Tasinkiewicz
1
Piotr Karwat
1 2
Norbert Żołek
1
Ihor Trots
1
Ryszard Tymkiewicz
1

  1. Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, Poland
  2. us4us Ltd., Warsaw, Poland

Instrukcja dla autorów

Article submission:

Articles for publication in Archives of Acoustics should be submitted via the journal website: https://acoustics.ippt.pan.pl.

Guidelines:

Author guidelines and submission requirements are available here: https://acoustics.ippt.pan.pl/index.php/aa/author-guidelines.

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